Disclaimer

This guide is meant to constitute Summaries of Material Modifications to the applicable Amgen benefit plan to which the changes apply. It constitutes an addendum to the Summary Plan Descriptions (“SPD”) for the applicable Amgen plans, which are available at the Amgen Benefits Center or by request by calling 800-97-AMGEN.

Coverage under each Amgen plan is determined under the terms of the applicable plan, as reflected in the SPD, this guide, and any other notice regarding coverage changes issued since the effective date of the applicable SPD. Nothing in this guide creates a right to be covered under any particular plan. Receipt of these materials does not guarantee that the recipient is a participant under any particular plan and/or otherwise eligible for benefits under any plan.

This guide is intended to provide an overview of certain benefit plans and programs offered to certain Amgen U.S.-based staff members. It does not constitute an offer of employment or compensation. Should any discrepancy exist between the plan or program documents governing an Amgen benefit and the information stated in this guide, the official plan or program documents, which are maintained by Human Resources, will prevail. You are encouraged to obtain copies of this information and review it in detail. Amgen reserves the right to change or terminate the programs and benefits described at any time without notice.